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Preparations of magnesium and vitamin B6 for neurasthenia. Magnesium and Vitamin B6: The Crucial Link You Need to Know! Magnesium is required to activate vitamin D

Another mineral that plays a large role in the healthy functioning of our body is magnesium. This element is involved in many processes - in energy production, glucose uptake, nerve signal transmission, protein synthesis, building bone tissue, regulation of relaxation and tension of blood vessels and muscles. It has a calming effect, reducing the excitability of the nervous system and enhancing the processes of inhibition in the cerebral cortex, acts as an anti-allergic and anti-inflammatory factor, protects the body from infection by participating in the production of antibodies, plays a significant role in the processes of blood clotting, regulation of the intestines, bladder and prostate gland, has an antispastic effect, promotes the removal of cholesterol from the body. It affects carbohydrate-phosphorus metabolism, protein synthesis, is involved as a cofactor or activator of many enzymes (alkaline phosphatase, hexokinase, enolase, carboxylase, etc.), has an alkalizing effect on the body, is in antagonistic relationships with calcium ions.

The daily requirement for magnesium in an adult is 0.4 g, in pregnant and breastfeeding women - 0.45 g. Magnesium is found in most foods.

The absorption of magnesium in the intestines inhibits excess calcium and fat. Under favorable conditions, up to 30-40% of magnesium is absorbed from food.

With magnesium deficiency neuromuscular excitability increases (muscle twitching, tetany, anxiety, fear, auditory hallucinations, tachycardia), loss of appetite, fatigue, dizziness, depressed mental state and fear, pain and tingling in muscles, chilliness, increased sensitivity to weather changes (especially hands and feet freeze), acute pains in the stomach, often accompanied by diarrhea. True, these same symptoms can be caused by other reasons, but if they are eliminated by an additional intake of magnesium, then the reason for their appearance is in it.

We get magnesium from food and drinking water, but only from hard water, where there is a lot of magnesium (there is little magnesium in soft water). Here are some interesting observations made by scientists. In Glasgow, for example, which has the softest water in England, deaths from diseases of the cardiovascular system are 50% higher than in London, where the water is very hard.

Our researchers have found that in St. Petersburg, where tap water taken from the Neva is soft, the number of cardiovascular diseases is higher than in regions with hard tap water.

Magnesium and vascular and heart diseases

In one study, scientists determined the magnesium content in the heart muscle (myocardium) of patients who died from a heart attack, and healthy people who died in car accidents. In those who died from a heart attack, 42% less magnesium was found in the damaged part of the heart than in the healthy, and in those who died in car accidents, no difference was found in the magnesium content in the muscles of different parts of the heart.

The founder of the theory of stress, Hans Selye, back in 1958 in animal experiments, proved that magnesium prevents the development of atherosclerosis. To one group of rats, he gave food poor in magnesium, and the other - rich. The animals from the first group soon developed atherosclerosis, and their blood cholesterol level was very high, while the animals from the second group did not have sclerotic changes in the vessels, cholesterol remained normal.

It is known that lecithin plays an important role in regulating the amount of cholesterol in the body. This amino acid is produced in the body by an enzyme containing vitamin B6, which, in turn, is activated by magnesium.

French doctors prescribed patients with vascular and heart disease, high cholesterol levels, manium lactate, and vitamin B6 in the morning and at night. For many, after a month, the cholesterol level dropped, the pain in the heart decreased.

Magnesium and diabetes

Magnesium deficiency is common in adults with diabetes, especially those who have to use insulin. Magnesium plays an important role in the release of insulin from the pancreas and thus in the regulation of blood sugar levels. A lack of this mineral in the body increases the risk of complications typical of diabetes, such as diseases of the heart, blood vessels and eyes.

Magnesium and stress

Unreasonable anxiety, increased irritability, blues - all these conditions can be associated with a lack of magnesium. Drink cocoa with a quarter teaspoon of magnesium oxide in the morning, and eat a teaspoon or tablespoon of magnesium-rich buckwheat honey at night with warm tea or milk.

Magnesium and chronic fatigue

Canadian researchers monitored a group of 100 adult men with complaints of unreasonable chronic fatigue, decreased interests in life, decreased sex drive. They were given 500 mg of magnesium sulfate (bitter salt), diluted in half a glass of water, in the morning and evening. Within 10 days, 87 people felt much better. Fatigue disappeared, a desire to live appeared, mood, sleep and appetite improved.

Magnesium and kidney stones

French doctors from the Paris Urological Clinic have found that magnesium, especially together with vitamin B6, is an effective remedy against oxalate kidney stones.

Taking within a month 300 mg of magnesium and 10 mg of vitamin B6 leads to partial, and sometimes even complete dissolution of kidney stones. This treatment is cheap, has no side effects, and is well tolerated. Naturally, magnesium in combination with vitamin B6 is also an excellent prophylactic against the formation of kidney stones.

Research in Finland has shown that kidney stones are very rare in people who eat mostly natural foods high in magnesium and calcium (whole grains and dairy products), despite the fact that the body receives an average of 4-5 g calcium per day. Calcium in this case is not deposited in the kidneys, since it is balanced by a sufficient amount of magnesium and protein, which bind excess calcium.

Magnesium and migraine

Magnesium supplementation has been shown to reduce headaches in people with persistent migraines, and it has also been shown to be effective in allergy-related and premenstrual headaches. When combined with vitamin B6, it normalizes mood during menstruation and relieves painful periods.

Magnesium and osteoporosis

Magnesium together with calcium stimulates the production of the thyroid hormone calcitonin and the parathyroid gland - the parathyroid hormone. These hormones play an important role in maintaining bone health and strength. If there is a lack of magnesium in the body, the strength and hardness of bones and teeth decreases. Lack of magnesium increases the risk of osteoporosis, a disease that leads to increased fragility and fragility of bones in older people, more often in women who have entered the period of menopause.

Physiological need for magnesium, mg per day:

In the methodological recommendations MR 2.3.1.2432-08 on the norms of physiological needs for energy and nutrients for various groups of the population of the Russian Federation dated December 18, 2008, the following data are given:

There is no upper limit for magnesium intake.

Foods rich in magnesium, Mg

Product nameMagnesium, Mg, mg% RSP
Cocoaovella701 175,3%
Cherry core598 149,5%
Seed kernels of common pumpkin and large-fruited pumpkin, dried592 148%
Sesame seed540 135%
Roasted almond kernel498 124,5%
Mustard powder453 113,3%
Wheat bran448 112%
Poppy seed442 110,5%
Cocoa powder425 106,3%
Roasted hazelnut kernels420 105%
Flax seeds392 98%
Brazilian walnut, not blanched, dried376 94%
Cotton seed342 85,5%
Rowan garden red331 82,8%
Sunflower seed317 79,3%
Rapeseed311 77,8%
Halva, takhinny303 75,8%
Halva, tahini chocolate290 72,5%
Roasted peanut kernels286 71,5%
Dried celery root284 71%
Cocoa mass282 70,5%
Cashew270 67,5%
Saffron264 66%
Buckwheat, food grain258 64,5%
Pine nut251 62,8%
Tahini-peanut halva243 60,8%
Mustard seed238 59,5%
Almond234 58,5%
Soybeans, grain226 56,5%
Whole Wheat Plates218 54,5%
Plum core210 52,5%
Pistachios200 50%
Nutmeg200 50%
Unfat soy flour200 50%
Semi-fat-free soy flour200 50%
Roasted coffee beans200 50%
Buckwheat unground200 50%
Natural coffee, ground200 50%
Apricot kernel196 49%
Peanut182 45,5%
Corn, high-lysine180 45%
Halva, sunflower vanilla178 44,5%
Wheat germ flour176 44%
Mash174 43,5%
Hazelnut172 43%
Seaweed170 42,5%
Hazel160 40%
Powdered milk, skimmed in sealed packaging160 40%
Dried boletus154 38,5%
Dry serum150 37,5%
Buckwheat groats150 37,5%
Barley, food grain150 37,5%
Fat-free soy flour145 36,3%
Pink salmon caviar141 35,3%
Nut chocolate140 35%
Powdered milk "Smolenskoe", 15.0% fat139 34,8%
Oats, food grain135 33,8%
Bitter chocolate133 33,3%
Dried beets132 33%
Macadamia nut, raw130 32,5%
Millet, food grain130 32,5%
Oat flakes "Hercules"129 32,3%
Chum salmon caviar129 32,3%
Sorghum127 31,8%
Chickpea126 31,5%
Dragee, nut124 31%

If you suffer from anxiety, you will most likely be interested in learning about a 100% natural remedy for calming the nerves. This remedy is a natural sedative created by nature itself. This mineral is involved in more than 300 biochemical reactions in the body that regulate various processes, from blood pressure and energy production to muscle relaxation and blood sugar levels. We all know that magnesium improves sleep, but how effective is it in fighting anxiety?

The relationship between magnesium, also known as the “natural relaxing mineral,” and anxiety is complex and depends on many factors. It is best to start explaining this connection with; many of us are likely not getting enough magnesium from our diet, which creates a magnesium deficiency and increases the risk of anxiety.

Magnesium deficiency and anxiety.

Magnesium deficiency is fairly common in the United States - so is anxiety ”Says Eileen Ruhoy, MD and PhD, an integrated neurologist and member of the MindbodygreenCollective community.

But how common is this problem, to be precise?

It is estimated that 50 to 90% of Americans suffer from magnesium deficiency. Reasons for this include the use of medication, soil depletion, and the standard American diet of predominantly refined and processed foods that contain little or no magnesium.

With over 3,700 molecules in the human body associated with magnesium, magnesium deficiency can affect health in many different ways. When it comes to anxiety, magnesium's role in the functioning of the parasympathetic nervous system (PNS) is of particular interest. The PNS is known as the "rest and digestion" system and is responsible for bringing the body back to rest.

Magnesium plays a key role in maintaining the health and functioning of the parasympathetic nervous system and the nervous system in general, and research shows that magnesium deficiency can stimulate the part of the nervous system that is responsible for the fight-or-flight response.

Magnesium and anxiety.

For those of us who suffer from generalized, social anxiety, panic attacks, PTSD, or other anxiety disorders, the idea that taking magnesium supplements will provide relief and substitute pharmaceuticals that have side effects and cause dependence.

But can magnesium really help deal with anxiety?

Research on this topic is still ongoing, but according to the best doctors in integrative and functional medicine, everything indicates that the answer to this question is yes.
Several studies have shown that taking magnesium is beneficial for anxiety, improves well-being, and brings feelings of peace, contentment, and resilience. , ”Says Rukhoi.

We are still not sure what exactly explains this connection, it is likely thatmagnesium is an important cofactor in the synthesis of and, two neurotransmitters that affect our mood and ability to relax. Magnesium also affects the activity of GABA, an important inhibitory neurotransmitter closely associated with anxiety (benzodiazepine drugs such as Xanax, the most popular anti-anxiety drugs, act on GABA receptors).
Several studies have shown a link between a lack of magnesium and worsening of the condition in mood disorders.

Research on magnesium and anxiety.

Marvin Singh, MD, holistic practitioner and member of the MindbodygreenCollective, says: “Magnesium is one of my favorite simple and natural remedies. An article published in 2016 noted the effectiveness of magnesium in treating anxiety, with positive results in cases of mild and PMS-related anxiety. .”

However, not all studies have been as convincing: ”Later, in 2017, a systematic review found that while there is evidence for magnesium's benefits in treating anxiety, stronger evidence is needed. , ”He explained.

How to take magnesium to relieve anxiety.

The bad news is that the results of studies on magnesium's effectiveness in fighting anxiety are not yet conclusive, the good news is that it is relatively safe to experiment with magnesium and many people use it with positive results.

Singh adds: “While we haven't yet figured out exactly how magnesium fights anxiety, taking magnesium is a great way to get yourself back into a relaxed state. You can take magnesium supplements in powder, capsule, or liquid form. It is worth noting that magnesium is part of many laxatives and loose stools may occur when taken.
This means that certain forms of magnesium, such as magnesium sulfate and oxalate, can cause diarrhea if taken too much.

To avoid this side effect, you can use, for example, pumpkin seeds, dark chocolate, and legumes such as black beans, etc. instead of additives.

What form should you take magnesium to combat anxiety?

If you are already thinking about buying magnesium supplements, you need to be prepared to be amazed at the variety of forms of this mineral. You should know that some forms are more effective.
So how should you take magnesium to relieve anxiety?

There are several magnesium salts, as well as magnesium threonate, citrate, gluconate, and citramate. Magnesium glycinate is an excellent choice, which does not cause indigestion, unlike almost all other forms.

What else should be taken care of for security reasons?

According to Singh: “If you suffer from kidney disease, heart disease, arrhythmias, and some other medical conditions, you should consult your doctor before starting magnesium supplements. .”

Basically, you should inform your doctor that you are about to start taking any new supplements, herbs, or fundamentally change your lifestyle or diet.

Another tip from an expert?

If you want to increase your magnesium intake, don't be limited to capsule or powder supplements. You can try magnesium oils or creams, and even Epsom bath salts, which are made from magnesium sulfate crystals.

These techniques are especially good because they additionally calm you and help you take time out for yourself, which increases your effectiveness in dealing with anxiety.

Translation from English

Composition, release forms and varieties of Magne B6

  • Oral tablets;
  • Oral solution.
  • Magne B6 forte is available in a single dosage form - oral tablets.

    Thus, as can be seen from the table, one Magne B6 forte tablet contains as many active substances as one full ampoule of solution (10 ml). And Magne B6 tablets contain half the active substances in comparison with the full ampoule of solution (10 ml) and Magne B6 forte. This should be borne in mind when calculating dosages for taking the drug.

    Magne B6 and Magne B6 forte tablets have the same oval, biconvex shape, painted in white shiny color. Magne B6 is packed in cardboard boxes of 50 pieces, and Magne B6 forte - 30 or 60 tablets.

    Therapeutic action

  • Congenital metabolic pathology, in which this element is poorly absorbed in the intestines from food;
  • Insufficient intake of the element into the body, for example, with malnutrition, starvation, alcoholism, parenteral nutrition;
  • Disorders of magnesium absorption in the digestive tract with chronic diarrhea, gastrointestinal fistulas or hypoparathyroidism;
  • Loss of large amounts of magnesium in polyuria (urine excretion in a volume of more than 2 liters per day), taking diuretics, chronic pyelonephritis, renal tubular defects, primary hyperaldosteronism or the use of Cisplastin;
  • Increased need for magnesium during pregnancy, stress, taking diuretics, as well as with high mental or physical exertion.
  • Vitamin B6 is a necessary structural element of enzymes that ensure the course of various biochemical reactions. Vitamin B6 is involved in the metabolic process and in the work of the nervous system, and also improves the absorption of magnesium in the intestines and facilitates its penetration into cells.

    Magne B6 - indications for use

    1. Magnesium deficiency identified and confirmed by laboratory tests, in which a person has the following symptoms:

  • Irritability;
  • Sleep disturbances;
  • Stomach and intestinal cramps;
  • Palpitations;
  • Fatigue;
  • Muscle cramps and pains;
  • Tingling sensation in muscles and soft tissues.
  • 2. Prevention of the development of magnesium deficiency against the background of an increased need for this element (pregnancy, stress, malnutrition, etc.) or its increased excretion from the body (pyelonephritis, taking diuretics, etc.).

    Magne B6 - instructions for use

  • Adults and adolescents over 12 years old - take 6 - 8 tablets per day (2 tablets 3 times a day or 4 tablets 2 times a day);
  • Children over 6 years old with a body weight of more than 20 kg - take 4 - 6 tablets per day (2 tablets 2 - 3 times a day).
  • The indicated daily amount of Magne B6 is divided into 2 - 3 doses per day, observing approximately the same intervals between them.

  • Adults and adolescents over 12 years old - take 2 - 4 ampoules per day (1 ampoule 2-3 times a day or 2 ampoules 2 times a day);
  • Children aged 6 - 12 years - take 1 - 3 ampoules per day (1/3 - 1 ampoule 3 times a day);
  • Children aged 1 - 6 years - take 1 - 4 ampoules per day, having previously calculated the exact dosage by body weight, based on the ratio of 10 - 30 mg of magnesium per 1 kg of weight.
  • The total daily dosage of the solution must be divided into 2 - 3 doses, trying to observe the same intervals between them.

    Magne B6 forte - instructions for use

  • Adults and adolescents over 12 years of age - take 3 - 4 tablets per day (1 tablet 3 times a day or 2 tablets 2 times a day);
  • Children 6 - 12 years old - take 2 - 4 tablets per day (1 tablet 2-3 times a day or 2 tablets 2 times a day).
  • The total indicated daily dosage of the drug must be divided into 2 - 3 doses.

    Impact on the ability to control mechanisms

    To treat an overdose of Magne B6, it is necessary to give a person diuretics in combination with plenty of water and rehydration solutions (for example, Rehydron, Trisol, Disol, etc.). If a person suffers from renal failure, then hemodialysis or peritoneal dialysis is necessary to eliminate the overdose.

    Interaction with other medicinal products

    Magne B6 during pregnancy

  • Spasms, cramps, muscle tics, pulling pains in the lower back or lower abdomen;
  • Dizziness, headaches, sleep disorders, irritability;
  • Arrhythmia, high or low blood pressure, palpitations, heart pain;
  • Nausea, vomiting, alternating constipation with diarrhea, cramps and abdominal pain;
  • A tendency to edema, low body temperature, constant chilliness.
  • Similar symptoms are found in a large number of pregnant women, which suggests that magnesium deficiency is widespread during childbearing. Knowing this state of affairs, gynecologists leading a pregnancy prescribe Magne B6 to women in regular courses for 3 to 4 weeks, even if this particular pregnant woman has not yet fully developed symptoms of magnesium deficiency.

  • Children aged 1 - 6 years with a body weight of 10 - 20 kg - take 1 - 4 ampoules per day, having previously calculated the exact dosage by body weight, based on the ratio of 10 - 30 mg magnesium per 1 kg of body weight per day;
  • Children aged 6 - 12 years with a body weight of more than 20 kg - take 1 - 3 ampoules a day (1/3 - 1 ampoule 3 times a day) or 4 - 6 tablets a day (2 tablets 2 - 3 times a day);
  • Teenagers over 12 years old - take 2 - 4 ampoules a day (1 ampoule 2-3 times a day or 2 ampoules 2 times a day) or 6 - 8 tablets a day (2 tablets 3 times a day or 4 tablets 2 times a day).
  • Clarification of the dosage not only by age, but also by body weight is very important. The fact is that even if the child is one year old, but his weight is less than 10 kg, then it is impossible to give him Magne B6 solution. Also, you can not give a child pills if he is 6 years old, but body weight is less than 20 years. In this case, a six-year-old child is given a solution in dosages for 1 to 6 years.

  • Teenagers over 12 years old - take 3 - 4 tablets a day (1 tablet 3 times a day or 2 tablets 2 times a day);
  • Children 6 - 12 years old - take 2 - 4 tablets a day (1 tablet 2-3 times a day or 2 tablets 2 times a day).
  • The indicated daily amount of Magne B6 and Magne B6 forte should be divided into 2 - 3 doses and drunk with meals. It is optimal to give the child all 2 - 3 doses of the drug before 17.00. The solution from ampoules for administration is preliminarily diluted in half a glass of still water, and the tablets are washed down with a glass of water.

  • Allergic reactions;
  • Nausea;
  • Vomiting;
  • Flatulence;
  • Diarrhea;
  • Constipation;
  • Abdominal pain;
  • Paresthesias - a feeling of running "goose bumps", numbness, etc. (occur only with prolonged use in high dosages);
  • Peripheral neuropathy (occurs only with prolonged use in high dosages).
  • Contraindications for use

    • Renal failure, in which creatinine clearance (CC) is less than 30 ml / min;
    • Age under 6 years old (only for Magne B6 and Magne B6 forte tablets);
    • Age less than 1 year (for oral solution);
    • Fructose intolerance (for Magne B6 and Magne B6 forte tablets);
    • Sucrase-isomaltase deficiency (for Magne B6 and Magne B6 forte tablets);
    • Glucose-galactose malabsorption syndrome (for Magne B6 and Magne B6 forte tablets);
    • Taking Levodopa;
    • Increased individual sensitivity to drug components.
    • On the Ukrainian pharmaceutical market , in addition to these, there are two more synonym drugs - Magnikum and Magnelact. Earlier Magnelakt was also sold in Russia, but now its registration period has expired.

    • Additive magnesium effervescent tablets;
    • Vitrum Mag chewable tablets;
    • Magne Positive tablets;
    • Magne Express granules for resorption;
    • Magnerot tablets;
    • Magnesium Diasporal 300 granules for preparation of oral solution;
    • Magnesium plus tablets.
    • Cheap analogues of Magne B6

    • Magnelis B6 - 250 - 370 rubles for 90 tablets;
    • Magnesium plus B6 - 320 - 400 rubles for 50 tablets.
    • The cost of Magnelis B6 and Magnesium plus B6 is almost two or more times lower than that of Magne B6.

      Magne B6 forte - reviews

      Magne B6 for children - reviews

    • Magne B6 tablets, 48 \u200b\u200bmg + 5 mg, 50 pieces - 550 - 660 rubles;
    • Magne B6 forte tablets, 100 mg + 10 mg, 30 pieces - 662 - 884 rubles;
    • Magne B6 solution, 10 ampoules of 10 ml each (100 mg + 10 mg) - 475 - 611 rubles.
    • Magnesium b6 aquion instructions for use

      Magnesium B6 is a vitamin complex (dietary supplement) aimed at maintaining nerve impulses and metabolism. Magnesium and vitamin B6 are found in every body, but if it is lacking, this medicine is prescribed. This complex will help the body cope with stressful moments in life and is useful for all ages.

      Vitamin-mineral complex is needed to maintain the body as a whole. Without it, calcium is also not assimilated. With a lack of this component, causeless fatigue, irritability appears, that is, it is bad for the whole body, and especially for the nervous system.

      The drug is prescribed for stress, during pregnancy, for the prevention of neuroses, when planning pregnancy and in the early stages, as well as with an increased tone of the uterus, reduces high blood pressure from the nerves.

      Composition, release form, cost

      Available in ampoules and tablets. Consists of 2 elements: magnesium lactate dihydrate plus vitamin B6.

    • 1 tablet contains 48 mg of magnesium and 5 mg of pyridoxine hydrochloride. Their color is oval, white. Available in boxes of 36 and 60 tablets.
    • 1 ampoule contains 100 mg of magnesium and 10 mg of pyridoxine hydrochloride. Packs contain 10 ampoules. It has been proven that a liquid preparation is best absorbed by the body. The contents can be drunk, diluted with water, or injections.
    • Producer Evalar, Aquion, Sistmatic (Russian).

      How much does the drug cost? The cost in the pharmacy of tablets (caps.) From 300 rubles for 50 pieces. And 10 ampoules from 250 rubles. Prices vary across the country.

      There are a lot of substitutes and drugs similar to this one. Namely: Magnelis, Magne B6, Doppelherz, Magnesia, Complivit (a preparation with many vitamins, including magnesium), Magnelis, Panangin, Solgar vitamin complex, Blagomax (B vitamins), Motherwort forte. Some are cheap and some are expensive. It depends on who produces.

      Some of these drugs contain other vitamins. Magne B6 and Magnesium B6 are one and the same, but the manufacturers are different. And the second one is much cheaper. They do not differ in action. But the replacement of the drug should be under the supervision of a physician. Maznesium is presented as effervescent tablets.

      Magnesium B6 and glycine are very good to take. This combination has a beneficial effect on the nervous system.

      Magnesium and vitamin B6 preparations what is the difference?

      They complement each other perfectly. Magnesium in the body is a source of energy and the correct functioning of all metabolic processes. Vitamin B6 also affects the nervous system, but through the synthesis of protein, hemoglobin and enzymes. It promotes the absorption of proteins and fats. Why talk about the differences, it is important to talk about the addition.

      Instructions for use

      Adults, both women and men, need to take 3-4 tablets 2-3 times a day. You can take a long time.

      If used in ampoules, then 3-4 ampoules. Dissolve the contents of the ampoule in a glass of water and drink. Drink the solution 2-3 times a day.

      You need to drink tablets after meals (so they are absorbed better) and drink plenty of water.

      Manual magnesium b6 forte

      The indications are the same as for the usual one: 3-4 tablets or ampoules per day.

      During pregnancy, breastfeeding, how to take?

      When breastfeeding (during lactation) it is not advisable to take this drug, as it is excreted in breast milk. It is also not recommended for infants under 12 months.

      Tablet, adult prescription

      In tablets, the medicine can be taken for children from 6 years old. The course of treatment is prescribed by a doctor. Usually the daily dose is 2-4 tablets during or after meals.

      Adults drink 3-4 tablets a day with a glass of water. On average, take up to 30 days.

      In ampoules, it is allowed to give babies from 12 months. It is necessary to give 10-30 mg for each kilogram of the child's weight. If you need to change the drug, be sure to consult your doctor. He will also say how much to drink in time. The drug is obtained as a syrup, as it has a sweetish taste.

      Reviews, contraindications

      It is contraindicated to use the medicine for renal failure, impaired glucose absorption, as well as for intolerance to the components.

      There are many reviews of this medicine, mostly positive. Sometimes you can find allergic reactions in children. Some doctors, for example, Komarovsky, advise taking magnesium for life, so the body will not take the necessary daily dose from the products. The official site will provide detailed instructions, where there is a photo of the medicine. The benefits of vitamins can be felt after a week of intake. There you can also find a children's gel containing a vitamin complex.

      What foods do contain magnesium?

      How much depends on nutrition. Buckwheat, soy, almonds, rice, bran, spinach, eggs, oatmeal and other foods containing potassium and magnesium are rich in the necessary microelements. One b6 will not cope, but in combination it must be taken for hair growth.

      Sometimes, pharmacies hold a “be healthy” campaign and sell vitamin complexes for less.

      The drug rarely has a negative effect on the body. The most common is allergies. In rare cases, there is gas and nausea.

      Compatibility with other drugs, alcohol

      Magnesium b6 is not compatible with taking levodopa. It impairs the absorption of the drug and its simultaneous administration with calcium. Alcohol flushes it out of the body. For obvious reasons, taking medication with alcohol becomes ineffective.

      One day there comes a moment in life when you realize that you know almost everything about many medicines. With age, you learn more and more new drugs, but the worst thing is that every month you take a significant part of the family budget to the pharmacy. And as luck would have it, the attending physician does not know cheap analogs, or simply forgets about them.

      At one point, I found out that there is a wonderful drug Magne B6, which my gynecologist prescribed to me during pregnancy.

      I then very often cramped my calves during sleep. I don’t know why I never did it during the day.

      Magne B6 price - 610 rubles for 50 tablets, of course shocked me. But it must be so because it is impossible to save on health. At that time, I took 4 tablets in two doses, the cramps were gone, and my mental balance returned to normal. And then the sudden mood swings of her husband have already gotten.

      The second time I wanted to buy Magne B6 when my daughter was about a year old, to calm her nerves. All the same, the child needs a calm mother.

      The seller in the pharmacy advised me to buy analogue of Magne B6 is Magnelis B6 costs 90 tablets 400 rubles... It turns out that Magnelis is not the only analogue, the company also produces Evalar Magnesium B6 (but I have no trust in this company), and there are also analogues for Blagomax and Aquion.

      There is also Magne B6 forte.

      Now I buy analogs, although Magne B6 is very good, but expensive.

      doctor-serdce.ru

      Magnesium b6 under stress

      Hello! The question is in the subject. The doctor recommended Magne B6, I suffer from insomnia, overwork, neuroses, anxiety, my pulse is fast, I eat little. I searched the Internet - mostly reviews about taking during pregnancy. I am interested in the experience of receiving in my situation. Has anyone had a positive experience? Were there any side effects? I would be very grateful for the feedback (and if you write down what indications they took). Thank.

      Stress. There was a very stressful period at work - everyone drank, even the men))) I don’t know what effect there is - one should not expect a momentary and strongly sedative effect from it.

      he helps. cumulative effect from it. you become calmer, the mood is better, cheerfulness. drink it, you will not regret it. no side effects

      Thank! I thought that there should be a cumulative and some kind of general strengthening effect, otherwise it would be possible to do with valerian or simple sedatives. But I am afraid of the side effects. I read on one of the sites that in case of an overdose, there may be cardiac arrest or paralysis !? I am going to drink three tablets for a month, I hope there will be no overdose during this time ..

      Because of stress, I drank in large doses of vitamins B1, B6, and B12. It even helped!

      In case of an overdose, these vitamins are excreted in the urine and K, so drink as much as you like. Only vitamin B12 is consumed no more than 2 g per day.

      Danai, and in what form did you drink these vitamins? Did you buy it in a complex or separately? I asked about Magne B6, this is magnesium with vitamin B6, there are no more B vitamins, but what is the effect of magnesium, I do not know for sure (there should be a strengthening one).

      In the complex, Neurobion are called.

      Danai, thank you, I'll ask the doctor too. But for some reason she immediately started talking about magnesium.

      judging by the name - something is also connected with nerves)

      Googled - a more serious drug than Magne, you definitely need to ask a doctor. There can be so many side effects. And the symptoms are more serious.

      I don't understand why they will not make the drug Magne B6 B1 B12? Not a single B6 and Magnesium strengthen the NS.

      12.desert decoration

      drinking water contains magnesium salts, mg is included in table salt, especially in sea water. mg is part of the pigment of plants. Without magnesium, there can be no green plants or animals that feed on them. mg is an essential component of ALL cells and tissues. magnesium and calcium are involved in NERVO-muscle excitability. large doses of magnesia salts do not cause poisoning, but act only as a laxative, magnesia salts (magnesium sulfate, also known as Epsom salt) can cause anesthesia if its concentration is exceeded by a multiple intravenously. Toxic phenomena are also observed with a decrease in the concentration of magnesium in the blood (twitching and convulsions). depletion of blood in children with magin is with rickets, as a result of which increased calcium prevails, which is not excreted from the body.

      13.desert decoration

      it is impossible to consume lepkarstvenny means from a kandachka - they all interact with each other in your internal factory. all your herbs, food and medications interact with each other and produce an effect that can be the opposite or unexpected. if you drink any medicine - drink only it, and not with handfuls of pills or willfully herbs-vitamins-dietary supplements. these are all individual combinations that no doctor will calculate for you, because no doctor is interested in this: specifically your ratio of vitamins-minerals-drugs in your specific blood at a given time. there are separate volumes about this - about their interaction. Herb, Nutrient and Drug Interactions

      desert decoration, thanks, in principle I know this, I'm just wondering to ask the doctor. but without the recommendation of a doctor I will not "prescribe" anything to myself

      I didn’t do it, I drank 2-3 tabs 3 times a day, I didn’t know the result.

      I was discharged from fatigue, it helped me very well, after a couple of days I became much stronger. But I have a genetic disease, defects of the cardiovascular system, the cardiologist prescribed it.

      16, thanks! what exactly do you have problems with the cardiovascular system? I have chronic vda, tachycardia, so I get tired very quickly and worry often.

      IF YOU BUY MAGNE V6 THEN ONLY TAKE FRENCH.

      thanks for the comments. Today I started drinking Magne B6 I'm sure my nerves will get better.

      i have been taking these pills for almost 3 weeks. stopped looking like boiled sausage: D used to sleep for 12 hours, now at 8 and wake up vigorously :)

      Why magnesium B6 is prescribed for hypertension

      The human body contains approximately 25 grams of magnesium. It is needed for the proper functioning of the nervous system, the conductive nerve complexes of the heart, protein synthesis, and strengthening of immunity. Magnesium dilates blood vessels, lowering pressure, and slows down hypertrophy of the heart muscle caused by arterial hypertension.

      A unique feature of this microelement is the ability to exert an anti-stress effect, creating a favorable psychological mood.

      Vitamin B6 transfers magnesium into the cell, enhances its absorption in the gastrointestinal tract. It increases the amount of a trace element inside erythrocytes, which is often reduced in hypertensive patients. Vitamin B6 is essential for the normal functioning of nervous tissue and the synthesis of neurotransmitters that contribute to a good mood: serotonin and norepinephrine.

      When to use magnesium B6

      According to the instructions, the drug must be taken with an already existing magnesium deficiency, or with conditions requiring its increased consumption. According to Russian researchers, a deficiency of this element in the diet is present in 70% of the population, American scientists say about 72%.

      In order to understand why magnesium deficiency is manifested by disruptions in the work of almost all organs and systems, you need to figure out what functions it performs.

      The clinical manifestations of a deficiency of this trace element can be grouped according to the predominant functional disorders.

      Increased excitability of cells

      Magnesium ions provide a resting phase for both nerve and muscle cells. Their deficiency disrupts the exchange of trace elements on cell membranes and leads to the fact that cells become over-excitable.

    1. The hyperexcitability of the cells of the nervous system leads to sharp fluctuations in mood, anxiety, tearfulness, and insomnia.
    2. An increase in the activity of heart muscle cells causes tachycardia and arrhythmias associated with the appearance of additional foci of excitation in the heart.
    3. Overexcitability of skeletal muscle cells causes muscle pain in the neck, back, muscle tension headaches, cramps of the calf muscles, spasms of small muscles of the hands (writing spasm, obstetrician arm)
    4. The increased excitability of vascular smooth muscle cells causes an increase in blood pressure and the resulting headaches.
    5. Hyperexcitability of smooth muscle cells of internal organs leads to abdominal pain, recurrent pain in women, stool disorders, when constipation is replaced by diarrhea, broncho- and laryngospasm, in pregnant women it provokes uterine hypertonicity, cervical spasm during childbirth.

    Disorders of energy reactions

    Magnesium participates in all metabolic processes, being a part of more than 300 enzyme complexes responsible for energy reactions in the body - the exchange of carbohydrates and ATP. Its deficiency causes disturbances in heat transfer - chilliness. Lack of energy provokes rapid fatigue with normal physical and mental stress.

    Neurotransmitter metabolic disorders

    Magnesium is needed for the correct exchange of neurotransmitters - substances that ensure the transmission of impulses between neurons.

  • Disruption of the metabolism of catecholamines - dopamine, adrenaline, norepinephrine - is the most important link in the pathogenesis of "diseases of civilization": coronary heart disease, arterial hypertension, type 2 diabetes mellitus.
  • Violation of serotonin metabolism leads to depression, anxiety, obsessive thoughts, loss of memory, attention, mood, impaired libido.
  • Disruption of the metabolism of gamma-aminobutyric acid leads to a lack of voluntary attention, hyperactivity, physical manifestations of anxiety (lack of air, palpitations), and a decrease in long-term memory.
  • Disruption of dopamine (dopamine) metabolism leads to a lack of energy, low level of motivation, impaired concentration, depression.
  • To determine magnesium deficiency, you can use a special test:

    Why Magnesium Deficiency Occurs

    Magnesium deficiency can arise primarily due to the genetic characteristics of the organism, when, with a normal magnesium content in the blood plasma, its penetration into the cells is difficult. Secondary deficiency can be associated with the characteristics of life and nutrition:

    1. Reduced magnesium intake;
    2. Impaired absorption in the gastrointestinal tract;
    3. Enhanced elimination;
    4. Endocrine disorders;
    5. Increased need for magnesium.
    6. Reduced consumption

      Typical for most modern people. A diet mainly consisting of potatoes, meat or poultry, dairy products is unable to become a sufficient source of micronutrients. The main sources of magnesium in the diet are "hard" water, fresh herbs, grapes, freshly harvested nuts. Filtration of water reduces the amount of trace elements contained, thermal processing of food leads to the formation of insoluble salts that are unable to be absorbed in the intestine, storage of nuts does not reduce the content of magnesium, but reduces its bioavailability.

      Reduced magnesium intake can also occur due to diets: both due to a decrease in the amount of food, and due to a change in its nature, when the list of "allowed foods" is limited. Fashionable low-carb diets almost completely eliminate foods containing this element from the diet.

      Decreased intestinal absorption

      Again, the most common reason is modern dietary habits. The excess fat in food, typical for fast food, disrupts the adsorption of magnesium in the gastrointestinal tract. The same happens with an excess of protein, calcium, alcohol.

      Bowel diseases also lead to a decrease in magnesium absorption:

    7. Prolonged diarrhea;
    8. Dysbacteriosis;
    9. Chronic duodenitis;
    10. Enterocolitis;
    11. Crohn's disease;
    12. Nonspecific ulcerative enterocolitis;
    13. Resection of part of the intestine.
    14. It can be a consequence of diseases such as:

    15. Gastrointestinal disorders;
    16. Nephrotic syndrome;
    17. Renal acidosis;
    18. Kidney pathology caused by diabetes.
    19. Also, some medications cause increased excretion of magnesium:

    20. Non-potassium-sparing diuretics;
    21. Laxatives;
    22. Hormonal contraceptives;
    23. Cytostatics;
    24. Cardiac glycosides;
    25. Glucocorticoids.
    26. Endocrine Disorders

      Magnesium deficiency is characteristic of the metabolic syndrome, manifested by impaired weight, decreased glucose tolerance, and arterial hypertension. It is also characteristic of type 2 diabetes mellitus, which is characterized by an increased content of not only sugar, but also blood insulin. Also, magnesium deficiency occurs in conditions such as:

    27. Hyperthyroidism (excess thyroid hormones);
    28. Hyperaldosteronism (excess of aldosterone synthesized by the adrenal cortex);
    29. Hypercatecholaminemia (excess of catecholamines synthesized by the adrenal medulla);
    30. Hyperparathyroidism (excess parathyroid hormone of the parathyroid glands).
    31. The increased need for magnesium occurs when:

    32. Stress (according to the Ministry of Health of the Russian Federation, 80% of Russian citizens live in a state of chronic stress);
    33. Active growth (children and adolescents);
    34. Increased physical activity;
    35. Increased sweating (hot countries, hot shops, steam room hobby);
    36. Pregnancy.
    37. How to use magnesium B6

      Since this trace element slowly accumulates in the body, you need to use magnesium B6 for at least two months in a row - provided that the patient is under 40 years old and does not suffer from chronic diseases. Patients over 40 or with chronic pathology need to take the medicine for at least six months. If the need to use magnesium is caused by emerging neurological disorders or depression, the drug should be used for at least a year in a row. In osteoporosis, the use of magnesium B6 becomes lifelong.

      Magnesium B6 and cardiovascular disease

      A lack of magnesium in the diet increases the likelihood of arterial hypertension. Prescribing magnesium B6 to hypertensive patients at a dosage (in terms of ions) of 240-960 mg per day led to a decrease in systolic pressure by an average of 18.7 mm. rt. Art., diastolic - by 10.9 mm. rt. Art.

      Residents of regions with "soft" water, with a reduced content of trace elements, more often develop myocardial infarction and sudden coronary death. Inside the cells of the myocardium of patients who died from cardiovascular pathology, the content of magnesium is reduced by half in comparison with healthy people.

      Magnesium addition at a dosage of 100 mg / day. reduces the likelihood of ischemic stroke by 8%.

      Taking the drug reliably slows down the development of atherosclerosis, even in people who do not follow a diet. 15 years after the correction of magnesium deficiency became a national matter in Finland and a special program was introduced, the number of myocardial infarctions has halved.

      Magnesium B6 and pregnancy

      You can find out the likelihood of magnesium deficiency during pregnancy using the following test:

      If necessary, fill the deficit, the daily dose for pregnant women is 10-15 mg of magnesium per kg of body weight per day. Taking magnesium B6 during pregnancy reduces the likelihood of the threat of termination, premature birth and the birth of children with reduced body weight.

      In pregnant women with uterine hypertonicity who took magnesium B6, the tone normalized after 2 weeks of administration.

      In pregnant women with arterial hypertension who took the drug, the frequency of gestosis was 3 times lower than in the control group, the frequency of use of antihypertensive drugs decreased 4 times, and the frequency of pyelonephritis decreased 6 times. These women did not experience fetal hypoxia during labor and the Apgar score of newborns was, on average, higher than in the control group.

      The age from which magnesium B6 can be used is limited by the form of the drug. It is believed that it is difficult for children under 6 years of age to take pills, so the tablet form is allowed only for children over this age. You can use the oral solution from 1 year old, with a child's body weight over 10 kg. Depending on the weight and needs, from 1 to 3 ampoules per day are used (5-10 mg of magnesium per kg of body weight per day, in one ampoule - 100 mg).

      A sufficient amount of magnesium in the body increases the adaptive capabilities of the child under stress caused by admission to kindergarten, school, change of the children's team.

      In children with ADHD, taking the medication for a month reduced the level of anxiety, aggression, and improved concentration.

      In what dosages to use magnesium B6

      Normally, about 400 mg of magnesium should be supplied with food daily (5 mg per kg of body weight / day). With a deficiency, the need for this trace element increases to 10-15 mg / kg / day, the same need for it in pregnant women. Children need 5-10 mg / kg / day.

      In preparations containing magnesium B6, instructions for use provide the following content of magnesium ions:

    38. Magne B6 - 48 mg;
    39. Magnesium B6 Evalar - 48 mg;
    40. Magvit (Belarus) - 50 mg;
    41. Magnelis B6 (Russia) - 48 mg;
    42. Magnistad (Russia) - 48 mg;
    43. Magnesium plus B6 (Russia) - 48 mg;
    44. Magnikum (Ukraine) - 48 mg;
    45. Magne B6 solution - 100 mg per ampoule;
    46. Magne B6 Forte - 100 mg.
    47. Thus, taking into account the intake of microelements with food and water, adults need from 6 to 10 tablets of magnesium B6 per day, children 4-6 tablets per day. Take the medicine 2-3 times, be sure to drink it with water (at least a glass). An ampoule of solution for oral administration should be diluted in half a glass of water, taken one 3 times a day

      When you can't use Magnesium B6

      Despite all the benefits of the drug for the body, there are conditions when its use is contraindicated:

    48. Individual intolerance;
    49. Phenylketonuria;
    50. Renal failure when creatinine clearance<30 мл/мин;
    51. Fructose intolerance (for dosage forms containing sucrose in the composition);
    52. Lack of the enzyme sucrase-isomaltase (similar);
    53. Glucose-galactose maladsorption syndrome;
    54. Concomitant use with levodopa;
    55. Tablets should not be used for children under 6 years old, solution - up to 1 year.
    56. It is not recommended to take the medicine at the same time as calcium supplements - as already mentioned, calcium reduces the absorption of magnesium. If necessary, first restore the balance of magnesium, only then - calcium.

      Magnesium B6 overdose

      If the kidneys are working normally, it is impossible to create an excess of trace elements and water-soluble vitamins (B6) in the body: the excess is excreted in the urine. If kidney function is impaired, magnesium may accumulate in the body, which manifests itself:

    57. Falling blood pressure;
    58. Nausea, vomiting;
    59. Decreased reflex activity, lethargy up to coma;
    60. Breathing disorder up to his paralysis;
    61. Decrease in the amount of urine up to anuria;
    62. Heart failure.
    63. Antibiotics from the aminoglycoside group dramatically increase the toxicity of magnesium.

      With prolonged overdose of vitamin B6, the following may occur:

    64. Sensitivity disorders, numbness of skin areas;
    65. Hand shake;
    66. Impaired coordination.
    67. These phenomena disappear after drug withdrawal.

      Initially, this medicine was produced by the French company Sanofi-Aventis under the name Magne B6. But given the exchange rate for many, this drug is too expensive. Studies that reliably prove that the original drug is absorbed better than similar products from other manufacturers, so it is quite possible to choose an analogue of magnesium B6 cheaper than the French one.

      It can be replaced by Russian analogues, such as "Magnesium plus B6", Magnestad, Magnelis, Russian-made. Another domestic drug - "Magnesium B6 Evalar" is produced both in tablet form and in the form of a syrup in a 100 ml bottle, approved for children from three years old. There are also analogues from the near abroad - the Ukrainian Magnikum and the Belarusian Magvit.

      Olga says: “I have been suffering from vegetative-vascular dystonia for 30 years. The slightest excitement - and the skin becomes whiter than chalk, and disgusting red spots appear on its surface. She was saved only by clothes with a high collar - turtlenecks and shirts with a collar to chin at any time of the year. She would have lived like a man in a case if the doctor had not prescribed this drug. I drank three packs, and when I realized that I no longer have any VSD, I almost burst into tears with joy. Along the way, I noticed that the night cramps in my legs, which appeared 1-2 times a month, disappeared. "

      Ksenia says: “After the birth of the baby, I did not sleep for three years. The child woke up several times a night, and when I brought him to the clinic for examination (by the age of three he did not speak clearly) - we were not received by any specialist, except for a neurologist - the guy screamed like a cut. The neurologist prescribed Magna B6 in ampoules, which tasted as sweet as syrup. In a month I can say that I see the results. The child says new words, and most importantly, he began to sleep peacefully in his own bed, without lifting me three times a night "

      Alena says: “She endured the first pregnancy normally, and during the second one, from the very beginning, the uterus was in good shape. My stomach was constantly pulling, I tried to move less - but how to do this when a two-year-old toddler was nearby? Magnesium B6 was prescribed to me to preserve the pregnancy. In the first trimester, two tablets three times, then the tone passed and the doctor said to reduce the dose to two times. I took it almost until the very birth, and everything ended well "

      Preventive course intake of magnesium B6 will help to avoid conditions such as chronic fatigue, depression, headaches. Taking the drug during pregnancy improves its course and reduces the risk of premature birth.

      In patients with cardiovascular disease, the agent slows down the development of the disease and reduces the likelihood of complications. The medicine will help children more easily endure the adaptation period in a new team or increased loads during exams.

      The medicine is produced by several manufacturers, which allows you to choose the best option for the price.

      progipertoniyu.ru

      Composition As part of Magne B6 in magnesium tablets, lactate dihydrate is contained in a concentration of 470 mg / tab. (equivalent to 48 grams of Mg ++), the content (pyridoxine hydrochloride) is 5 mg.

      Evalar offers tablets "Magnesium B6", which help to improve the state of the nervous system.

      Magnesium-B6: instruction. Magnesium tablets are good. Take Magnesium B6 with. Magne b6, tab., Coated Indications, contraindications, dosage regimen, side effects, overdose, drug interactions. SANOFI WINTHROP INDUSTRIE, manufactured by SANOFI WINTHROP INDUSTRIE, manufactured by CHINOIN Pharmaceutical and Chemical Works Private. Magne B6 tablets. 1 tablet contains magnesium lactate dihydrate 470 mg (which corresponds to 48 mg of magnesium), pyridoxine hydrochloride 5 mg. Excipients: sucrose, heavy kaolin, acacia gum, carboxypolymethylene 954, talc, magnesium stearate, Carnauba wax (powder), titanium. Magne B6 (magnesium. Applications, tablets. Together with instructions for use.

      Heavy kaolin, carboxypolymethylene, sucrose, magnesium in the form of hydrosilicate (talc) and stearate, acacia gum are used as auxiliary components. The composition of the tablet shell: acacia gum, sucrose, titanium dioxide, trace amounts of hydrous magnesium silicate and carnauba wax in powder form. The oral solution contains 186 mg of magnesium lactate dihydrate and 936 mg of magnesium pidolate (which corresponds to a total Mg ++ content of 100 mg), 10 mg of pyridoxine hydrochloride. Auxiliary components: sodium disulfite and saccharinate, cherry and caramel flavor, purified water. Composition of the tablet Magnesium B6 Forte (Antistress): 618.43 mg magnesium citrate, 10 mg pyridoxine hydrochloride, anhydrous lactose, magnesium stearate and hydrosilicate, macrogol 6000, hypromellose, titanium dioxide. Release form Pharmacological forms of the drug: biconvex oval tablets in a white film shell with a shiny smooth surface (10 pieces in blisters of aluminum foil and PVC, 5 blisters per pack); transparent, brown solution for oral administration with a pronounced caramel smell (in 10 ml ampoules, 10 ampoules in a cardboard packing insert); white oval biconvex tablets in a film shell (15 pieces in blisters made of aluminum foil and PVC-PE-PVDC, 2 or 4 blisters per pack). Pharmacological action Pharmacotherapeutic group: B vitamins in combination with minerals.

      The action of the drug is aimed at replenishing the magnesium deficiency. Pharmacodynamics and pharmacokinetics Magnesium (Mg) is an important biogenic element, which is present in significant quantities in all tissues of the body, is a cofactor of most metabolic processes and ensures the normal functioning of cells. In particular, this element is necessary for the biotransformation of creatine phosphate into ATP - nucleoside triphosphate, which plays the role of a universal supplier of energy in living cells of the body. Without magnesium, protein cannot be synthesized normally. The element takes part in muscle contraction (including maintaining the normal function of the heart muscle), regulates the transmission of impulses in the nerve fibers, promotes vasodilation, stimulates the secretion of bile, increases the motor activity of the intestinal tract, which in turn promotes excretion from the body. Magnesium enters the body with food.

      Its deficiency can be primary (due to hereditary pathologies) or secondary. Secondary magnesium deficiency is usually associated with: a violation of the diet (poor in vitamins and minerals diet, exclusively parenteral nutrition, chronic alcoholism); with an increase in a person's need for a microelement during intense physical or mental activity, during periods of intensive growth, during pregnancy, during stress, excessive loss of Mg through the kidneys (for example, with chronic, diuretic abuse, treatment); with impaired absorption of Mg in the gastrointestinal tract due to hypoparathyroidism, chronic diarrhea, etc. Vitamin B6 (pyridoxine) improves the course of metabolic processes, including in the brain tissues.

      As a result, the efficiency of the brain increases, mood and memory improve. In addition, the presence of pyridoxine in the composition of Magne B 6 improves the absorption of Mg from the digestive tract and its distribution in the cells of the body. If the serum Mg concentration is in the range of 12 to 17 mg / L, it is said to be moderately deficient in Mg.

      An indicator not exceeding 12 mg / l is evidence of a severe micronutrient deficiency. No more than half of the ingested dose of Mg is absorbed in the digestive tract. 99% of the trace element is located in the intracellular space, while about 66% of the intracellular Mg is distributed in the bone tissue, the remaining amount in striated and smooth muscles. Mg is excreted mainly in the urine (about a third of the dose taken). Indications for use The indication for the use of Magne B6 is a confirmed Mg deficiency (both isolated and associated with other deficiency conditions).

      Symptoms of insufficient intake of Mg are fatigue and irritability, sleep disturbances, heart palpitations, stomach and intestinal cramps, tingling sensations in the muscles, and muscle spasticity and soreness. Contraindications Contraindications to the use of Magne b6 are: severe renal failure (conditions in which the clearance does not exceed 30 ml per minute); impaired absorption of glucose and galactose, fructose intolerance, sucrose-isomaltase deficiency (only for the tablet form of the drug); simultaneous administration of an antiparkinsonian agent; ; hypersensitivity to substances contained in tablets / solution. In pediatrics, tablet forms of the drug are prescribed from the age of six, the solution in ampoules is allowed from the year. Due to the risk of developing hypermagnesemia, the drug should be prescribed with caution to persons with moderate renal failure. Side effects The drug very rarely causes side effects. Allergic (including skin) reactions are possible no more often than in 0.01% of cases. Sometimes taking Magne B 6 is accompanied by side effects from the digestive tract (flatulence, abdominal pain, diarrhea, nausea, vomiting), but it is impossible to establish the frequency of their occurrence from the data available today.

      Instruction on Magne B6 Before taking Magne B6, you should consult your doctor. The average course duration is one month. The treatment is stopped immediately after the blood Mg concentration is normalized. The medicine is taken with meals 2 or 3 times a day. If the drug is prescribed during pregnancy, the dose is selected individually by the attending physician. Magne B6 tablets: instructions for use Magne b6 tablets are taken 6-8 pieces per day.


      Table of contents [Show]

      Fifty years before the first use of magnesium in medicine (1906), Fyodor Mikhailovich Dostoevsky wrote in his diary: “… I turned around all night, slept for half an hour. The gloomy dawn did not bring joy. Longing and anxiety holds the heart with its claws. I am writing, but a lump rolls up to my throat, I can't breathe, tears stand in my eyes, and my hand is cramping from constant writing. " A modern neurologist, having read such words, will immediately say: there are all the signs of magnesium deficiency in the body, diet and magnesium-containing preparations are indicated.

      What is magnesium for?

      Magnesium is an element that is involved in most key physiological processes. It is extremely important for the normal functioning of cells, muscles and especially nervous tissue. The human body is not able to synthesize magnesium on its own and therefore receives it only through food. Magnesium is necessary for all systems of the body, without exception, it "starts the work" of many enzymes involved in energy, protein, carbohydrate and fat metabolism. Only 300 biochemical processes directly depend on it, and indirectly - several orders of magnitude more. For example, magnesium plays an important role in the prevention of diabetes.


      The great importance of magnesium lies in the fact that it serves as a natural anti-stress factor, inhibits the development of excitation processes in the central nervous system and reduces the body's sensitivity to external influences, relieves the symptoms of anxiety and irritability. The fact is that physiologically all extreme influences lead to an increase in the release of adrenal hormones, an increase in adrenaline in the blood. This removes magnesium from the cells via the kidneys. Therefore, almost all stress can be treated with magnesium.

      In addition, independent research by Russian scientists - professors of the International Institute of Microelements "UNESCO" A.A. Spassov, Ya. I. Marshak - showed that the restoration of normal magnesium levels reduces cravings for alcohol, drugs and smoking, and especially effective in the treatment of addiction therapy with "heavy artillery" - special magnesium-containing drugs.

      In addition, magnesium is known to prevent the formation of calcium oxalate stones, which is the most common cause of urolithiasis. Studies have shown that consuming 500 mg of magnesium per day reduced the incidence of stone formation by 90 and a half percent.

      Mineral-norm


      For all its importance, magnesium is also the most vulnerable trace element in our body. Its balance is very easy to upset. The daily requirement of an adult for magnesium is 300-350 mg. Since this trace element in the body is not produced on its own, then this entire dose must be supplied with food. But, unfortunately, over the past 100 years, we have begun to receive much less magnesium. This is most often due to improper nutrition. In the modern diet, there are very few products with a maximum magnesium content - unrefined cereals, as well as fresh fruits and vegetables. The situation is aggravated by the fast food system, which is based on the use of refined food, excess sugar and salt, as well as products that remove magnesium from the body - for example, phosphoric acid contained in Coca-Cola and other lemonades, various preservatives and other "E ".

      What are the causes of magnesium deficiency?

      Magnesium deficiency can be due to the following factors:

      Inadequate dietary intake: poor diet, low calorie diet, alcohol consumption, drinking soft water, chronic or prolonged diarrhea. Increased need: for example, during growth, pregnancy, breastfeeding; with intense physical exertion, in situations of stress and increased mental stress; during the rehabilitation period after serious illnesses and injuries. Taking certain medications can also be the reason for its deficiency (diuretics, cardiac glycosides, antibiotics (especially aminoglycosides), corticosteroids, oral contraceptives, hormone replacement therapy, anti-inflammatory drugs, etc. Low solar insolation: winter period of the year, work in dark rooms.


      What Symptoms Indicate Magnesium Deficiency?

      The first symptom is usually increased fatigue, a tendency to depression. Other manifestations include twitching of the eyelids, feeling tense, memory impairment, falling asleep or insomnia, night cramps, sometimes numbness, dizziness, irritability, palpitations, heart problems, feeling short of breath, and a lump in the throat. Magnesium deficiency can lead to a vicious cycle: a deficiency of this mineral contributes to the development of stress, which in turn increases its deficiency. A more pronounced lack of magnesium can lead to the development of cardiovascular (arrhythmia) and gastrointestinal disorders.

      Comments (visible only to specialists verified by the MEDI RU edition)

      Magnesium - one of the most important elements for the body. Without it, cells are unable to function, because it is present in absolutely all tissues of the body. Muscle contraction, translation of nerve impulses, metabolic reactions - magnesium is involved in all these processes. That is why, to normalize the patient's condition, the doctor prescribes Magnelis B6 with VSD, which includes Magnesium.

      Magnesium appears in the body due to the absorption of food. If the diet is violated for any reason, then the person is forced to take diuretics. And also with stress, pregnancy and increased various loads on the body, there may be a lack of magnesium in the body.

      Syndromes and symptoms with VSD have no connection with physical disorders. The causes of these manifestations in VSD have not yet been fully understood. Therefore, this condition can in no way be distinguished as a separate disease. For this reason, when treating VSD, symptomatic treatment of Magnelis B6 is prescribed.

      The biggest mistake in the treatment of VSD is the treatment with magnesium preparations of those symptoms that must be treated with the use of antidepressants. A magnesium deficiency in the body must be confirmed by laboratory tests, because an excess of magnesium can also lead to very negative consequences.

      If mental disorders are not properly treated, they will progress. For example, panic attacks can easily transform into agoraphobia, which, in turn, negatively affects the patient's work and quality of life. Prolonged depression can be the consequences of this condition.

      Magnelis B6 with VSD is often prescribed as a drug for stress. This approach is not entirely correct. It is possible to take Magnelis B6 with VSD with a laboratory established lack of magnesium.

      Magnelis B6 is also prescribed in the presence of the following symptoms:

      • anxiety and fears;
      • sleep disorders of varying severity;
      • rapid fatigue and the associated disability;
      • excessive irritability;
      • bad mood during the main period of time;
      • spasms in the muscles and in the gastrointestinal tract.


      For adults, a three-time daily intake of Magnelis B6 is attributed. During it, you need to drink 6-8 tablets of Magnelis B6. It is best to take Magnelis B6 with VSD directly in the process of taking a meal, washing down the tablets with water.

      How much Magnelis B6 to drink with VSD for children depends on body weight. If the weight is over 20 kg, then the number of tablets per day can reach 4-6 pieces.


      Side effects in the process of taking Magnelis B6 with VSD can manifest themselves in the form of nausea, vomiting, flatulence and abdominal pain. Allergic reactions also have the ability to manifest themselves when using Magnelis B6.

      Magnelis B6 poisoning with VSD can occur with renal failure. Its symptoms are vomiting and nausea, low blood pressure and impaired reflexes after taking Magnelis B6. The most serious consequences after taking Magnelis B6 are cardiac arrest and coma at the time of VSD. In severe poisoning of Magnelis B6 with VSD, intensive care measures should be prescribed.

      During the period of bearing a child, Magnelis B6 with VSD is taken in strict accordance with the doctor's recommendations. During breastfeeding, it is better to refrain from taking Magnelis B6 with VSD.

      One of the most important functions of Magnelis B6 in VSD is that it serves as an anti-stress factor. This is due to the fact that Magnelis B6 slows down the processes of excitation of the central nervous system and, because of this, the patient stops responding too sharply to external stimuli.

      The nervous system is extremely sensitive to a lack of magnesium. A decrease in it in the body is manifested by nervousness, unreasonable fears and anxiety, insomnia and fatigue, and frequent headaches.

      Magnesium, together with vitamin B6, normalizes the nervous system during stress, depression and stress. Any stress significantly increases the body's daily need for magnesium, which is why patients need Magnelis B6 for VSD.



      This combined magnesium preparation belongs to the second generation of magnesium-containing substances and is absorbed in the body as well as Magnelis B6. Magne-B6 is effective in a set of measures (along with antidepressants) for neuroses. Together with anticonvulsant drugs, this drug is good for treating convulsive conditions. For sleep disorders, it is used together with sleeping pills and as an analogue of Magnelis B6 for VSD.

      Alcohol abuse is one of the main causes of magnesium deficiency in the body. Although taking Magnelis B6 with VSD does not prohibit alcohol intake, doctors still do not recommend taking them at the same time. It will be best to refuse to take alcoholic beverages during the course of treatment with Magnelis B6 with VSD. When interacting with alcohol, Magnelis-B reduces its effectiveness up to the complete disappearance of the therapeutic benefit in VSD. Allergic reactions to the drug can be aggravated by the incompatibility of Magnelis B6 with alcohol.

      Such a state with VSD, like panic attacks, is also to some extent associated with a magnesium deficiency. After all, if we talk about the fact that it is magnesium that protects the body from stress, then a panic attack arises precisely on the basis of anxiety and fear. That is, under stress. Therefore, magnesium for panic attacks is necessary in the form of the use of Magnelis B6.

      Patient reviews on the use of Magnelis B6 at the time of VSD:

      Anna, 42 years old.

      “I suffered for 6 years, until it turned out that it was the lack of magnesium that provoked panic attacks. A couple of Magnelis B6 tablets with VSD per day and I am already quite comfortable being outside my apartment. Thank you Magnelis B6. "

      Anton, 55 years old.

      “I had terrible cramps from a lack of magnesium. Magnelis-B6 was prescribed by a doctor after any tests. Magnelis B6 helped solve the problem. "

      Dmitry, 52 years old.

      “I have no other diagnosis, except for VSD. At the same time, panic attacks are simply terrible - chills, nausea, tremors in the body. After the start of the use of Magnelis B6 with VSD, it became easier. "

      Nina, 31 years old.

      “I have long been diagnosed with VSD, magnesium preparations were periodically prescribed along with all sorts of other drugs. It's hard to say which ones had a stronger effect, but the doctor told me that Magnelis B6 should be taken in conjunction with other drugs to alleviate the condition with VSD.

      Jeanne, 49 years old.

      “It was a difficult period at work, plus constant overwork throughout the year. Insomnia started constantly from the nerves. Then I began to take Magnelis B6 and eat right. It became much better and, although I had to work in the same intense mode, I didn't feel so tired anymore thanks to Magnelis B6. "

      Magnesium deficiency in the body can lead to the appearance of various diseases. Lack of many minerals (iodine, zinc, chromium, etc.) leads to various diseases.

      But in the era of toxicity of the world around us, magnesium is:

      • One of the most common minerals for its lack in the human body.
      • One of the most dangerous for human health when it is lacking in the body.

      Everyone needs to know about this.

      Moreover, there is good news.


      Magnesium deficiency in the human body is easy to fix!

      1. Most people are deficient in magnesium.

      1) The USDA states that about 60% of adults do not consume the average daily requirement of this mineral.

      2) Scientists believe that 80% of people do not get enough of this mineral from food and are sick due to this deficiency, which leads to the accumulation of toxins in cells and blood.

      2) Many experts call this the daily and necessary minimum. They believe that the dose should be individual for different people.

      And this is due to the different amount of stress (measured by the level of cortisol) and the amount of toxins in the body, and, probably, in some cases it can be 1000 mg.

      3) Toxic substances in the body have a destructive effect on organs, tissues and cells.

      Magnesium participates in many biochemical reactions in the body to remove toxins from the body.

      The presence of toxins in the body leads to a decrease in magnesium from the body.

      1) To the appearance of a variety of allergic reactions.

      2) Frequent colds and flu. Now the World Health Organization believes that the incidence of influenza is associated in most cases not with the virus itself, but with the body's response to the chemical stress caused by the virus.

      3) Diabetes mellitus (diabetes mellitus is associated with toxic stress, chemical stress and a deficiency of certain substances, especially magnesium).

      4) Heart disease, stroke and many other diseases. You may find the article "Dangerous Signs of Magnesium Deficiency" helpful.

      5) Scientists have found that psychological stress leads to the movement of magnesium from the intracellular to the extracellular space, while the excretion of magnesium in the urine increases and its amount in the body decreases.

      6) The connection between magnesium and depression.

      Depression is easily and best treated with magnesium.

      Magnesium levels in the body are key to mental and emotional health.

      7) Alcohol, stress, and magnesium.

      During times of stress, some people reduce stress by increasing their alcohol consumption.

      And alcohol lowers magnesium levels in the body.

      Alcohol intake increases the excretion of magnesium in the urine by 260% (this is not a mistake, two hundred and sixty percent) above the baseline values.

      And this happens within a few minutes after drinking alcohol.

      So decide now whether alcohol is good for your health!

      On the other hand, by increasing the consumption of magnesium, the need for alcohol, that is, the desire to drink, decreases.

      It is useful to know this in Russia!

      "8)" Magnesium deficiency in the body also appears in children.

      In 2002, the American Journal of Epidemiology published the results of a study of the diets of 2566 children aged 11-19 months. It was shown that less than 14% of boys and 12% of girls had an adequate intake of magnesium.

      9) Magnesium deficiency can be a big problem.

      When describing magnesium deficiency, signs of its deficiency, different levels are distinguished.

      Marginal (borderline) magnesium deficiency can easily translate into more significant health problems when stressful events trigger additional magnesium loss.

      In extreme situations, a decrease in the amount of magnesium in the body can lead to cardiac arrest.

      Therefore, during stressful situations, do not drink alcohol if you want to live. Drink herbs - adaptogens and drink them with magnesium.

      Read about this in the article "Seven herbs reduce the level of the stress hormone cortisol"

      10) Even a moderate magnesium deficiency can lead to increased sensitivity to noise, nervousness, irritability, depression, mental disorders, seizures, insomnia.

      Why do Americans always smile? Indeed, in 60 - 80% of Americans, scientists noted a magnesium deficiency. Or do they have this deficit less than the residents of Russia?

      Go to the subway, bus, tram. Almost all people are gloomy, tired and nervous.

      Every person now has problems and taking more magnesium will not solve them, but it will be easier to endure all the hardships of life.

      11) How much magnesium is in water?

      The World Health Organization (WHO) has recommended drinking water with 25 to 50 mg of magnesium per liter to prevent death from heart attack and stroke.

      American bottled water contains 5 mg per liter, which is significantly less than the recommended dose.

      Many brands of bottled water are sold in Russia.

      In "Royal Water", which is used for coffee machines, the magnesium content is not more than 20 mg per liter.

      In water "Shishkin Les" - 0.055 mg per liter.
      In Arkhyz water - 5 - 20 mg per liter.
      In the water "Frutonyanya" - 5 - 35 mg per liter.
      In Borjomi water - 50 mg per liter.
      In water "Essentuki 4" - less than 100 mg per liter.
      In water "Essentuki 17" - less than 150 mg per liter.
      In water "Essentuki 20" - less than 100 mg per liter.

      As you can see, medicinal - mineral waters have doses of magnesium recommended by WHO, and ordinary drinking waters have low concentrations of magnesium.

      12) Magnesium deficiency causes serotonin deficiency.

      Serotonin is a neurotransmitter, it is also called "the hormone of good mood" and "the hormone of joy." It has many functions in the body.

      But its lack is dangerous to health, aberrant behavior (this is a cardiological term, arrhythmias, etc.), depression and other undesirable phenomena for life may occur.

      Another article wrote that dietary factors can play a significant role in the origin of ADHD and that magnesium deficiency can lead to destructive behavior.

      13) A significant number of researchers have shown that 60 - 90% of illnesses are directly caused or aggravated by stress.

      Indeed, numerous studies have shown that stress is linked to underlying medical conditions such as heart disease, high blood pressure, and diabetes.

      Currently, few experts doubt that stress can kill, which means that a lack of magnesium can send a person to the grave.

      And it is so easy to add to the body!

      This concludes this article, but I will write more about magnesium.

      I wish you have adequate levels of magnesium in your body and good health.

      In order for health to be normal, the body needs to regularly receive a number of vitamins and minerals. Most of them come with food. Theoretically, if a person is absolutely healthy and eats right, then he does not need a special diet that involves the inclusion in the diet of a large number of foods containing one or another useful element, much less taking special medications and biological additives that include such elements. However, the rhythm of modern life and the quality of food do not allow us to saturate the body with everything it needs, which can lead to malaise, weakness, or even some kind of disease. Especially important are nutrients that support the work of the cardiovascular system, including magnesium and vitamin B6. Their deficit must be replenished, otherwise serious health problems may arise. This can be done using special preparations.

      This is a drug that is a synthesis of magnesium and vitamin B6. These two elements are ideally combined, and it is thanks to their complex action that the maximum therapeutic effect can be obtained. In addition, vitamin B6 enhances the absorption of the mineral, which is the main ingredient.

      The drug supports the health of the cardiovascular, nervous, muscular and skeletal systems of the body.

      Scientists, after conducting a study, came to the conclusion that the diet of a modern person cannot provide him with the required amount of magnesium. On average, the deficit is 70%.

      A lack of the mineral can provoke unpleasant symptoms and the development of serious diseases. Deficiency of vitamin B6 also does not affect well-being in the best way, since this vitamin is of considerable importance for the normal functioning of the nervous system. Magnesium B6 helps to replenish these nutrients.

      Unhealthy diet is the main cause of magnesium deficiency in the body

      Table: daily consumption rate

      * If one tablet contains 470 mg of magnesium lactate dihydrate, which corresponds to 48 mg of magnesium. The drug has instructions with an exact indication of the dosage.

      Medicines are prescribed to normalize body functions and eliminate symptoms of magnesium deficiency. In this case, the decision on the need to take the drug should be made by the doctor. Sometimes it is prescribed even in cases where normal levels of the mineral have been detected in the blood and its serum.

      1. To restore the nervous system in the event of any, even, at first glance, minor disorders, ranging from mild irritability, and ending with severe forms of vegetative vascular dystonia and cardioneurosis.
      2. To normalize blood pressure in hypertension.
      3. To eliminate pain in the heart and heart rhythm disturbances. If the cause of heart ailments lies not in a functional disorder, but in a serious heart disease, then the supplement is prescribed in combination with other drugs.
      4. For the treatment of muscle cramps.

      The need for taking Magnesium B6 is assessed, among other things, by the woman's well-being during menstruation and menopause. The hormonal background is directly related to the nervous system, which is why they have a significant effect on each other. For this reason, the premenstrual symptom occurs. Another common phenomenon: vegetative-vascular dystonia during menopause or at some periods of the cycle. The appearance of this kind of ailments may indicate the need for the appointment of "recharge".

      Magnesium deficiency immediately affects the state of health, manifesting itself with headaches and other unpleasant symptoms.

      It is imperative to ensure that there are no signs of deficiency during pregnancy. During this period, a woman's heart already has a heavy load. In addition, a lack of magnesium provokes spasms and cramps in the muscles (pregnant women often complain about this), which is why it can cause a miscarriage, as it leads to an increase in the tone of the uterus and an increase in contractions of its smooth muscles.

      Magnesium B6 is as good for men's health as it is for women. It is known that a deficiency has an extremely negative effect on the production of testosterone, which has a direct effect on the entire body of a man, from the genital area to the psycho-emotional one. Therefore, men cannot ignore the lack of these nutrients.

      During the period of growth, and especially puberty, the body spends a lot of useful elements for its development, as a result of which their deficiency may arise. This macronutrient has a direct effect on the formation of the cardiovascular and nervous system, therefore its deficiency can be extremely dangerous and provokes the development of various diseases. For this reason, the slightest suspicion of a deficiency is the basis for determining its level in the blood and the appointment of Magnesium B6.

      A list of symptoms that occur with magnesium deficiency in the body:

      • headache;
      • tachycardia;
      • arrhythmia;
      • muscle cramps;
      • irritability;
      • insomnia;
      • premenstrual syndrome;
      • lazy bowel syndrome;
      • anxiety and neurasthenic disorders;
      • photosensitivity and sensitivity to noise;
      • hypertension;
      • an increased level of platelets in the blood.

      The listed symptoms can occur not only in case of deficiency, but also if the body lacks some other useful substances. In addition, they are common to a variety of diseases. Therefore, their occurrence cannot unambiguously indicate the need for supplementation. In order to confirm the suspicions that have arisen, it is necessary to pass tests for the level of magnesium in the blood.

      Magnesium supports the functioning of various organs and body systems

      Contraindications

      Rarely, but still there are people who are not allowed to specifically consume magnesium B6. Their body is able to assimilate the substances included in it only in the composition of food.

      1. Allergic reactions and individual intolerance.
      2. Phenylketonuria.
      3. Renal failure and other kidney diseases.
      4. Age up to 6 years (when it comes to solution - up to 1 year).
      5. Breastfeeding period.
      6. Taking laxatives. In this case, magnesium can cause serious digestive distress.
      7. Diabetes. This is because sucrose or fructose are often present in magnesium B6 tablets as additional ingredients.
      8. The use of tetracycline antibiotics or calcium preparations. Together with magnesium, antibiotics cannot be absorbed normally. In the case of calcium, the opposite is true: magnesium is not absorbed. If there is an urgent need to take magnesium along with the listed drugs, you need to ensure that an interval of at least 3 hours is maintained between the intake.

      Their occurrence is extremely rare, but, nevertheless, such a possibility should be taken into account.

      1. Allergic reactions.
      2. Disruption of the digestive organs (stool disorders, nausea and vomiting, etc.).
      3. Peripheral neuropathy (unpleasant tingling sensations in the limbs, numbness and goosebumps).

      Healthy kidneys will try to remove excess drug, but when their function decreases, extremely unpleasant symptoms can occur:

      • nausea and vomiting;
      • hypotension;
      • respiratory disorders;
      • anuria;
      • numbness of the limbs.

      Severe cases of overdose are life-threatening. Respiratory paralysis or cardiac arrest may occur. Of course, these are isolated cases caused by an individual body's response to the drug, combined with the inability of the kidneys to excrete it due to a decrease in their function. Nevertheless, the manufacturers of magnesium preparations warn that this is possible.

      After cases of overdose, the drugs should not be taken further.

      Not everyone is ready to take pills. First, it's inconvenient. Secondly, it contains additional ingredients, including artificial additives. Thirdly, there is an opinion that the body, learning to work at the expense of drugs, begins to be lazy to work independently over time (not quite, of course, but it does not do it as efficiently as it could). Therefore, replacing tablets with natural products containing the necessary nutrients is a very sensible decision.

      However, this is not possible in all cases. If a small deficiency is identified, then, of course, a change in diet can restore the level of this substance. If the deficiency is critical, then, most likely, you still have to resort to taking Magnesium B6. In addition, sometimes the problem lies not in improper nutrition, but in the increased excretion of magnesium by the body. For example, this can happen as a result of treatment with hormonal drugs. They are able to reduce the level of macronutrient, along with the level of potassium, to a critical level and provoke the development of serious cardiovascular diseases. With hormone therapy, you should immediately start taking the supplement in the form of pills, since even the diet that is maximally saturated with this trace element will not be able to maintain its level in the norm.

      If the treatment of food deficiency is possible, then the diet must include in large quantities:

      • nuts (all types);
      • sunflower seeds;
      • beans;
      • green pea;
      • lentils;
      • buckwheat, oat and millet groats;
      • parsley and dill;
      • garlic;
      • carrot;
      • spinach;
      • arugula;
      • banana;
      • raisins;
      • persimmon;
      • dates;
      • prunes;
      • eggs;
      • a fish;
      • milk and dairy products;
      • meat (pork and beef).

      Analogs and generics

      It's no secret that the pharmaceutical market offers drugs with the same composition at different prices. These medicines have different names and are produced by different manufacturers. As for magnesium preparations, there are also several of them. Here are just a few of them: Magnesium B6, Magne B6, Panangin, Asparkam, Magnerot, Magnelis B6 forte, Magnistad, etc.

      Video: overview of magnesium preparations

      If a person wants to maintain health, then he must ensure that his body, in addition to other useful substances, receives magnesium B6. With a deficiency of this trace element, it is necessary to adjust the diet or even resort to taking special drugs. However, you do not need to take them thoughtlessly, since an overdose is no less dangerous for the body than a lack of this substance. The opinion that everything unnecessary will simply be excreted by the body without causing any harm is erroneous. In order not to harm yourself, you need to carefully approach the calculation of the dosage, monitor the body's reaction to taking medications, and consult a doctor.

      A.S. Kadykov
      Professor
      S.N. Busheneva
      doctor

      The name "magnesia" is already found in the Leiden X papyrus (3rd century AD). It probably comes from the name of the city of Magnesia in the highlands of Thessaly. Magnesian stone in ancient times was called magnetic iron oxide, and magnes - a magnet. It is interesting that the original name "magnesium" was preserved only in Russian thanks to the textbook of Hess, and at the beginning of the 19th century, other names were proposed in a number of manuals - magnesia, magnesia, bitter earth.

      The total magnesium content in the human body is about 25 grams. It plays an important role in the formation of over three hundred enzymes. Magnesium takes part in energy and electrolyte metabolism, acts as a regulator of cell growth, is necessary at all stages of the synthesis of protein molecules. The role of magnesium in the processes of membrane transport is especially important. Magnesium helps to relax muscle fibers (musculature of blood vessels and internal organs). The most important value of magnesium is that it serves as a natural anti-stress factor, inhibits excitation processes in the central nervous system and reduces the body's sensitivity to external influences.

      It is believed that 25-30% of the population lacks magnesium from their diet. This may be due to modern processing technologies and the use of mineral fertilizers when growing vegetables, leading to a deficiency of magnesium in the soil.

      Chronic magnesium deficiency is often observed in patients with diabetes mellitus, arterial hypertension, atherosclerosis, epilepsy, osteoporosis, etc. A number of physiological conditions are known, accompanied by an increased need for magnesium: pregnancy, breastfeeding, a period of intensive growth and maturation, old and senile age, hard physical labor and physical activity in athletes, emotional stress, frequent and prolonged (more than 30-40 minutes per session) staying in a sauna, not getting enough sleep, flying and crossing time zones. Magnesium deficiency occurs with caffeine, alcohol, drugs, and certain medications, such as diuretics, which help remove magnesium in the urine.

      Our nervous system is sensitive to magnesium levels in the body. Its reduced content can cause anxiety, nervousness, fear, as well as insomnia and fatigue, decreased attention and memory, in some cases - seizures, tremors and other symptoms. People often complain of "causeless" headaches.

      Magnesium (especially in combination with vitamin B6) has a normalizing effect on the state of the higher parts of the nervous system during emotional stress, depression, neurosis. This is no coincidence. Stress (physical, mental) increases the need for magnesium, which causes intracellular magnesium deficiency.

      Magnesium deficiency worsens with age, reaching a maximum in people over 70. According to the European Epidemiological Study of Cardiovascular Diseases, plasma magnesium levels below 0.76 mmol / L are considered an additional (for example, arterial hypertension) risk factor for stroke and heart attack. An imbalance of Ca2 + and Mg2 + ions is one of the serious causes of blood clots in blood vessels. The use of magnesium preparations helps to reduce the tendency to form a blood clot. Magnesium, for example, enhances the antithrombotic effect of aspirin.

      It is believed that magnesium plays a positive role in inhibiting the process of atherosclerosis.
      Taking into account the latest data on the prevalence of magnesium deficiency in residents of large cities, its content in the blood is determined in neurological patients with chronic fatigue syndrome, vegetative-vascular dystonia, as well as in depression and asthenia. Normally, the serum magnesium content in children varies from 0.66 to 1.03 mmol / l, in adults from 0.7 to 1.05 mmol / l.

      In healthy people, the daily requirement for magnesium is 350-800 mg. With a magnesium deficiency, its additional administration is required at the rate of 10-30 mg per kilogram of body weight per day. In addition to dietary correction, medicinal preparations are also used. The saturation time of tissue depots during magnesium therapy is 2 months or more. The choice of drugs for correction is well known - these are inorganic and organic magnesium salts. The first generation of magnesium-containing preparations included inorganic salts. However, in this form, magnesium is absorbed by no more than 5%, stimulates intestinal peristalsis, which often leads to diarrhea. The absorption of magnesium in the gastrointestinal tract is increased by lactic, pidolic and orotic acids, vitamin B6 (pyridoxine), and some amino acids.

      The second generation of magnesium-containing preparations is much better absorbed and does not cause dyspepsia and diarrhea. Magne-B6 belongs to modern combined drugs.

      The anti-anxiety effect of Magne-B6 allows it to be included in the complex therapy of depression (in conjunction with antidepressants), convulsive conditions (in combination with anticonvulsants), sleep disorders (in conjunction with hypnotics), and also to use the drug as an additional means for preventing and leveling lung excitatory effects of brain metabolism activators. Magnesium therapy is a rather promising direction in the treatment of night sleep disorders of various origins, especially in patients with asthenic and anxiety conditions. The vasodilating effect of magnesium ions allows Magne-B6 to be used in combination with antihypertensive agents. However, a decrease in blood pressure in response to magnesium administration is achieved only in patients with magnesium deficiency.